Spoligotype signatures in the Mycobacterium tuberculosis complex.

نویسندگان

  • E M Streicher
  • T C Victor
  • G van der Spuy
  • C Sola
  • N Rastogi
  • P D van Helden
  • R M Warren
چکیده

Evolution of the direct repeat region in Mycobacterium tuberculosis has created unique spoligotype signatures specifically associated with IS6110-defined strain families. Spoligotyping signatures may enable the analysis of the strain population structure in different settings and will enable the rapid identification of strain families that acquire drug resistance or escape protective immunity in drug and vaccine trials.

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عنوان ژورنال:
  • Journal of clinical microbiology

دوره 45 1  شماره 

صفحات  -

تاریخ انتشار 2007